Carry The One by Carol Anshaw.

A novel that, after several brief initial chapters on a wedding and a tragic car accident following, follows the lives of the occupants of the car that kills a 10 year old girl, including the life of the drunken driver.

Very strong.  At times over the years the guilty connection between the car occupants and the increasingly-distant catastrophe victim grow tenuous, but Anshaw completes each of the five lives she follows so densely one begins to forget the accident itself.

Anshaw is witty and has a compelling eye for detail.  Mostly set in Chicago, the narrative covers 30 years, from the early 80s until shortly after 9/11.